GLP-1RA gastrointestinal side effects
What are the GI side effects of GLP-1RA Medications, like Ozempic?

In treating T2D diabetes patients, our Texas Diabetes & Endocrinology board-certified experts may recommend medication to help lower blood sugars in addition to lifestyle changes. Some injectable forms of medical therapy, known as GLP-1RA medications, have been trending in the news lately due to their role in weight-loss management

These drugs go by popular brand names such as Ozempic, Mounjaro, and Trulicity. 

While the medicines are very effective for many patients and can be used safely with regular monitoring, recent data reports that there can be serious gastrointestinal (GI) side effects in rare cases. 

GLP-1RA Gastrointestinal Side Effects

GLP-1RAs help to slow the speed at which food passes through the stomach, causing people to feel fuller longer and better regulate blood sugar levels.

This form of drug treatment however can also lead to GI side effects (like severe nausea and vomiting) in some people. 

A new study in the Journal of the American Medical Association recently revealed that those taking GLP-1RAs for weight loss were at an increased risk of GI issues such as:

  • Biliary disease
  • Gastroparesis
  • Pancreatitis
  • Bowel obstructions

These conditions reportedly contributed to many patients electing to discontinue use on their own.

A study published in the American Journal of Managed Care found that approximately 50% of those being evaluated and who were on GLP-1RA meds stopped them within a year. 

What are the consequences of stopping GLP-1RA meds without direction from your doctor?

While initially stopping these medications may not have immediate health repercussions,  it could likely have an effect down the road. 

Failure to properly manage diabetes could lead to complications from continuously elevated blood sugars – like nerve damage, vision loss and worsening kidney function. Stopping these medications could also lead to regaining any lost weight, which typically also worsens insulin resistance and blood sugar control.

With any new therapy, it is important to follow all instructions carefully and as directed by your doctor.   Our endocrinology experts will always discuss treatment options with you and any potential risks or side effects. 

If you ever experience side effects from your diabetic medications, please contact us right away so that we can evaluate the situation and discuss effective alternatives. 

Contact Us Today to Learn More about  Diabetes and Weight Loss Management

If you’d like to schedule an appointment with Texas Diabetes & Endocrinology and discover how our diabetes services  and weight-loss management program can help you lead a full and active life, contact us at (512) 458-8400 or request an appointment online.  

Don’t forget to follow us on Facebook and Instagram and check back with us each month as we provide you helpful wellness and health information.

Endocrinology Top Doctors
Congratulations to our 2024 Top Doctors

We welcomed the new year celebrating board certified endocrinologists Valerie Espinosa, MD and Lindsay Harrison, MD for being recognized on the 2024 Top Doctors list in Austin Monthly magazine. 

Dr. Espinosa joined Texas Diabetes and Endocrinology in 2005. She is board certified in endocrinology and metabolism and active in clinical research concerning diabetes, obesity and thyroid disease. 

Dr. Harrison joined Texas Diabetes and Endocrinology in 2013. She is board certified in internal medicine, endocrinology, diabetes and metabolism. 

Austin Monthly Top Doctors is an annual peer-nominated recognition of the best physicians in Travis, Williamson and Hays counties. Using an online survey, physicians are asked to nominate colleagues who they would trust with the medical care of themselves or their family. We are could not be prouder to have our physicians included on this list.  

Congratulations Dr. Espinosa and Dr. Harrison!

For more information on our comprehensive endocrinology services, schedule a consultation with one of our board certified endocrinologists by requesting an appointment online or call (512) 458-8400. 

Don’t forget to follow us on Facebook and Instagram and check back with us each month as we provide you with helpful health and wellness information.

heart disease prevention
Heart Disease and the T2D Connection

People with diabetes are twice as likely to have heart disease or suffer a stroke than non-diabetics. 

In fact, the American Heart Association recently issued its  Heart Disease and Stroke Statistics for 2023 which found that one in three adults in the U.S. have three or more risk factors that contribute to cardiovascular disease, metabolic disorders, and/or kidney disease. This supports the likelihood that if you have diabetes, you may also be prone to heart disease. 

How does diabetes contribute to heart disease?

High blood sugar levels can damage the blood vessels and nerves surrounding the heart, leading to deterioration and serious damage over time. 

Texas Diabetes team of endocrinology specialists can not only help manage your diabetes, but we can monitor your heart health and assess your risk for cardiovascular disease too. 

Our endocrinology experts recommend several tips to both manage your diabetes and support a healthy heart.  

Five Tips to Manage Diabetes While Supporting Heart Health 

1.         Maintain a healthy weight. Discuss your goal weight with your physician for optimal health and remember that steady and gradual weight loss is the safest route. 

2.         Exercise regularly. Regular exercise, at least 150 minutes per week for adults, helps boost circulation and lower blood glucose levels. Find a sport or active hobby that you enjoy so that you’re more likely to stick with it!

3.         Follow a heart healthy diet. Eat right-sized portions and try using the Diabetes Plate Method to guide your meals. Load up on brightly colored, non-starchy vegetables, lean proteins, and whole grains. 

4.         Look after your mental health. Effectively managing stress can help keep hormones and blood pressure in check, both of which lead to better diabetes management and heart health. Find things that help you to unwind, like walks, reading, meditation, or warm baths, and build them into your daily schedule as you would any other important activity. 

5.         Take medications as prescribed. Make sure you are taking all of your diabetes medications and insulin as directed by your physician to support healthy blood pressure and cholesterol levels. And stay on top of all your numbers that you should be regularly monitoring, such as your A1C, blood glucose levels, and blood pressure. 

In addition to managing your diabetes, we can help assess your risk for cardiovascular disease so that we can best determine your treatment.  

Heart Disease Prevention at TD&E

At Texas Diabetes and Endocrinology, we conveniently offer cardiovascular risk assessment testing in our clinics which includes: 

  • Advanced Lipid Test: this diagnostic evaluates more than traditional testing (cholesterol, LDL & HDL) in order to measure abnormal lipid levels that are often missed 
  • Coronary Artery Calcium (CAC) Test: this is a non-invasive procedure similar to an X-ray that detects calcium/plaque in the arteries that feed your heart which can help diagnose coronary artery disease before showing signs or symptoms 

Our physicians and advanced practice providers are trained in lipidology and have extensive experience in treating cholesterol disorders. 

Contact Us Today to Learn about Managing Diabetes and Preventing Heart Disease 

If you’d like to schedule an appointment with Texas Diabetes and Endocrinology and discover how our diabetes treatment and heart prevention services can help you, contact us at (512) 458-8400 or request an appointment online.  

Don’t forget to follow us on Facebook and Instagram and check back with us each month as we provide you helpful wellness and health information.

hormone therapy for thyroid disease in seniors
Dr. Jean Chen on Over Treating the Thyroid and Cognitive Decline in Older Adults

The thyroid  is a small gland at the front of your neck that produces hormones which help control several different organ systems. If it’s either underactive (hypothyroidism), or overactive (hyperthyroidism), it could cause serious health issues such as weight changes, fatigue, anxiety/depression, or osteoporosis and may require medication to help better regulate it. 

New research shows though that some hormone medications used to treat thyroid conditions, if administered in excess, may contribute to cognitive disorders in older adults.

This particular study evaluating more than 65,000 patients appeared recently in the JAMA: Journal of the American Medical Association and showed that those 65 years and older who received thyroid hormone therapy were at an increased risk for developing dementia and other cognitive issues, especially those who were aggressively dosed. 

Our endocrinology experts at Texas Diabetes and Endocrinology treat many hormonal issues, including those affecting the thyroid. One of our board-certified endocrinology specialists, Dr. Jean Chen, shared her thoughts on this study for an article in Medscape.

The article stressed the importance of being vigilant when dosing hormone therapy for older adults to avoid the cognitive consequences of overtreatment. 

“Taking a cautious approach to prescribing thyroid hormone therapy for older patients is

paramount,” said Dr. Chen. “All medical providers need to be aware that the 65 and older population does not need to be treated as aggressively with their thyroid hormone.” 

“We are finding more and more complications from overtreatment rather than benefit in this (senior) population.”

Dr. Chen also explained that symptoms of hyperthyroidism can often mimic those of another condition, so it is important to obtain a thorough diagnosis from a primary care physician before automatically adopting any hormone therapies. Our endocrinologists frequently work in close collaboration with other care providers to arrive at the most accurate diagnosis and treatment plan to suit your personal needs. 

Thyroid Specialists in Austin

Our team of endocrinology specialists is experienced at diagnosing and treating all issues affecting the thyroid including hypothyroidism, hyperthyroidism, thyroid nodules, and thyroid cancer. We provide convenient thyroid ultrasound imaging and biopsy procedures on-site in our clinics and will work with you to formulate the most effective treatment plan possible.

Contact Us Today to Learn More about Managing Your Diabetes and Hormones 

If you’d like to schedule an appointment with Texas Diabetes and Endocrinology and discover how our comprehensive endocrinology services can help you, please contact us at (512) 458-8400 or request an appointment online.  

Don’t forget to follow us on Facebook and Instagram and check back with us each month as we provide you with helpful wellness and health information.

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