Tag: endocrinology

Spotlight on Obesity Clinical Research Trials
Posted on by Leslie Branon

Clinical research trials test the effectiveness of a new treatment or therapy on volunteer patients during a development phase before being introduced to the public. 

Participating in clinical research trials is an integral part of our practice and provides Central Texans an opportunity to receive new and promising treatment and/or cutting edge technology.

Research participants do not have to be a current Texas Diabetes patient to enroll in a clinical trial and we are actively recruiting patients for obesity studies – both those with diabetes and those without diabetes. 

There is no cost for participation, and the provided medications and study-related labs and exams are free. In addition, most studies will compensate patients for their time and travel.

Obesity Clinical Research 

Our board-certified endocrinologists have served as principal investigators in obesity trials over the past decade to help patients with their weight loss management. Obesity is a serious condition that can lead to a variety of health problems including diabetes, heart disease or respiratory issues.

“We see research as a very important part of what we do at Texas Diabetes,” says endocrinology expert Dr. Thomas Blevins. “We are currently studying the next generation of obesity agents just as we studied the GLP-1 agonists that are available today.”

Dr. Blevins recently served as a co-author for a published study on a promising innovative obesity agent called Oforglipron.

“We are now offering a new obesity trial for an investigational drug that is being developed as a chronic weight management treatment,” explains Dr. Blevins. “To qualify for this study, participants must be living with obesity and have at least one weight-related health issue other than type 2 diabetes.”

Anyone interested in learning more about this study can contact our research department to learn more. 

Patient Success with TD&E Research Trials 

One TD&E patient who has participated in obesity clinical research is 61-year-old Carla. Three years ago, she was prediabetic and wanted help managing her weight, so she opted to participate in a three-year study that involved weekly shots, counting calories, and working with a TD&E study coordinator and registered dietician to help her reach her goals.

She completed the clinical research trial in December 2023 with the following positive results:

  • Shedding 130 pounds
  • Losing her prediabetic status
  • Eliminating her blood pressure medicine 

TD&E applauds Carla for her diligent efforts to tackle weight loss while contributing to the greater advancement of medicine and science! 

She encourages other patients looking for additional ways to improve their condition to take the first step by contacting TD&E to see what clinical research trials are available.

“The Texas Diabetes research team was my greatest cheerleader,” shares Carla. “Someone was always available to help keep track of my health and advise me every step of the way.”

To those who sign up for clinical studies, Dr. Blevins thanks them and says, “we are indebted to the patients who volunteer to take part in our research trials at Texas Diabetes & Endocrinology.” 

Clinical Research Opportunities at TD&E

You can learn more about our research department and currently enrolling clinical trials here. Please feel free to contact us at (512) 334-3505, option 4, to speak to a research coordinator about our enrolling studies.

Don’t forget to follow us on Facebook and Instagram and check back with us each month as we provide you helpful wellness and health information.

diabetes complications
Decreasing Your Risk for Diabetes Complications 
Posted on by Leslie Branon

The CDC estimates that more than 29 million American adults are currently living with diabetes.

Diabetes is a chronic disease that affects how your body makes and processes glucose, or blood sugar. While it is possible to lead a very full and active life with diabetes if your diet and medications/insulin are carefully managed, there is still the potential for serious complications to occur. 

What are some common diabetes complications? 

Diabetes complications usually develop gradually over time with the disease. It is important to monitor your blood glucose levels vigilantly and stay on track regarding regular check-ups with your endocrinologist.

Some of the most common diabetes complications that our endocrinology experts see include: 

  • Heart disease: diabetics are twice as more likely to suffer from heart disease and stroke than others due to damaged blood vessels and nerves surrounding the heart 
  • Kidney disease: elevated blood sugar levels over time can lead to chronic kidney disease, the need for dialysis, and even kidney failure 
  • Blindness and eye issues: diabetes can also damage blood vessels in the eye/retina (diabetic retinopathy) 
  • Neuropathy: diabetic neuropathy, or nerve damage, is pain or numbness that stems from blood vessels and nerves (typically in the legs and feet) lacking sufficient oxygen or nutrients hijacked by high blood sugar 
  • Non-healing foot and leg ulcers: sores and infections that appear on the legs or feet due to poor circulation and elevated glucose levels can be hard to treat and may lead to amputation in extreme cases

If you notice signs or symptoms of any of these diabetes complications, speak with your endocrinologist right away about solutions to treat and manage them effectively. 

Decreasing Your Risk for Diabetes Complications

Along with keeping regularly scheduled appointments with your physician, and taking medications/insulin as instructed, here are five other ways to help prevent from developing severe diabetes complications: 

1.         Follow a healthy diet of lean proteins, brightly colored fruits and vegetables, and whole grains. 

2.         Exercise regularly and aim for at least 150 minutes of physical activity per week. 

3.         Maintain a healthy weight and BMI (Body Mass Index) and speak to your doctor about what that optimal weight should be. 

4.         Manage your blood pressure and cholesterol levels and make sure they are within healthy and normal ranges. 

5.         Stop smoking to avoid additional damage to your heart and lungs beyond what high blood sugar levels may already contribute. 

With proper management, and prompt attention to any symptoms you are experiencing, you can keep your diabetes complications to a minimum.

Contact Us to Help Manage your Diabetes, Osteoporosis and Thyroid Conditions 

If you’d like to schedule an appointment with one of our endocrinology specialists in Austin or Round Rock please contact us at (512) 458-8400 or request an appointment online.  

Don’t forget to follow us on Facebook and Instagram and check back with us each month as we provide you helpful wellness and health information.

menopause and diabetes
What should you know about menopause and diabetes?
Posted on by Leslie Branon

There’s no doubt that cases of diabetes are on the rise. In fact, experts predict that by the year 2050, one in every three adults in the United States could suffer from this chronic disease that disrupts hormones, affects how the body reacts to food and sugars (glucose), and can lead to obesity, heart disease and stroke if not managed properly.  

At Texas Diabetes & Endocrinology (TD&E), our board-certified endocrinology experts treat diabetes, along with other endocrinology disorders like osteoporosis, every day. 

One group in particular that is experiencing an uptick in diabetes diagnoses is menopausal women.  During menopause, estrogen levels decrease (because of diminishing ovarian reserves) which can cause weight gain leading to potential insulin resistance and difficulty metabolizing glucose. 

New research now shows that Type 2 Diabetes (T2D) is one of the most common health risks associated with postmenopausal women (up to age 55 years). 

This particular study evaluated 2,295 postmenopausal women and surveyed them and their propensity towards diabetes via blood tests, physical exams and measurements, and in-person interviews. 

Here’s what was found:

  • Lower levels of the hormones estrogen and progesterone are key factors in contributing to more cases of T2D in women over the age of 40
  • The prevalence of T2D increased in women with a greater BMI (Body Mass Index) and also elevated cholesterol levels 
  • Mood swings and hot flashes associated with menopause can cause poor sleep which is also a contributing factor to obesity, and therefore diabetes 

One of the most important things women can do to prevent diabetes brought on by menopause is to get screened.

“In support of recommendations by the American Diabetes Association, we suggest getting tested for diabetes every three years after the age of 45 if you are overweight or have a family history of the disease,”  says TD&E board-certified endocrinologist and diabetes expert Dr.  Jean Chen.

“Additionally, adopting a healthy lifestyle including eating a well-balanced, low fat and low cholesterol diet, and exercising regularly incorporating weight-bearing workouts can go a long way in helping to prevent diabetes as women approach menopause and this transitional phase in life.”

Diabetes Treatment for Women in Menopause 

Hormone Therapy (HT), or hormone replacement therapy and estrogen supplements, is the standard treatment for women experiencing severe menopausal symptoms. HT can help balance and regulate hormones which are depleted and improve symptoms like hot flashes, help with insulin function, and decrease the potential for developing diabetes. 

HT has also been shown to reduce the risk of osteoporosis (weakened bones), another common condition as women reach menopause. 

At TD&E, we offer individualized treatment plans to help effectively manage your diabetes through tools like weight management and insulin pumps.  We also provide extensive treatment options for osteoporosis and fracture prevention.  

Contact Us to Help Manage your Diabetes, Osteoporosis and Thyroid Conditions 

If you’d like to schedule an appointment with one of our specialists at Texas Diabetes & Endocrinology and discover how our diabetes services  and other endocrinology therapies can help you lead a full and active life, please contact us at (512) 458-8400 or request an appointment online.  

Don’t forget to follow us on Facebook and Instagram and check back with us each month as we provide you helpful wellness and health information.

What’s the link between osteoporosis and the gut biome? 
Posted on by Leslie Branon

May is Osteoporosis Awareness Month. This condition, marked by severely weakened bones, is one that our board-certified endocrinologists treat daily here at Texas Diabetes & Endocrinology (TD&E).

While it is commonly known that calcium helps to strengthen bones and protect against osteoporosis, new research shows that good gut health (or the gut biome) can also play a large role in osteoporosis prevention and boosting bone density (the amount of minerals stored in bones to make them strong). 

The gut biome is the complex mix of microorganisms that live in the body’s intestines and helps with immunity and food processing. 

What is the connection between osteoporosis and the gut biome? 

A new study recently published strongly supports previous findings that a healthy gut biome can in fact improve bone density and help protect against osteoporosis.  This important connection between the gut biome and the body’s bones is known as the gut-bone axis. 

Data shows that eating fruits and vegetables high in Vitamin C can increase production of the bone-making cells that protect them from weakening, or possibly fracturing and breaking, which is typically associated with osteoporosis. This conversion of Vitamin C into powerful bone-boosting cells takes place in the gut. 

Research also continues to show that foods rich in calcium (like dairy products) and high in protein (lean meats and legumes) help to fortify bones and keep them strong. 

Additionally, tracking certain types of bacteria that exist in the gut biome, and then supplementing with lacking bacteria known to boost bone-making cells, may become an increasingly more common option for osteoporosis prevention.  This can be facilitated by a physician recommending a mix of synbiotics (probiotics combined with prebiotics) to promote healthy bacteria in your gut biome.

According to TD&E endocrinologist Dr. Mauli Shah, along with keeping your gut check in health, other ways you can help prevent osteoporosis are with “regular exercise (weight bearing or resistance exercises are best), and taking Vitamin D and calcium supplements.” 

When should you see a doctor for osteoporosis?

Dr. Shah offers the following recommendations for when you should visit a doctor, or endocrinology expert, regarding your risk for osteoporosis:

  • All women 65 years of age and older 
  • Post-menopausal women with certain risk factors, such as those who’ve had a previous fracture or been treated with steroids
  • People who have a family history of osteoporosis or hip fractures 
  • People with rheumatoid arthritis
  • Women who have entered premature menopause or men with low testosterone

Osteoporosis Treatment at Texas Diabetes

Our endocrinology and osteoporosis experts will help develop the right treatment plan for you to address your unique bone health needs. We typically recommend lifestyle modifications to start, like getting more exercise and eating well. Then we’ll determine what combination of dietary supplements, medications, and/or injections and IV infusions are best suited to protect and strengthen your bones. 

Contact Us to Help Manage your Osteoporosis, Diabetes and Thyroid Conditions 

If you’d like to schedule an appointment with one of our specialists at Texas Diabetes & Endocrinology and discover how our diabetes services  and other endocrinology therapies can help you lead a full and active life, please contact us at (512) 458-8400 or request an appointment online.  

Don’t forget to follow us on Facebook and Instagram and check back with us each month as we provide you helpful wellness and health information.

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